Description
It works by inhibiting nucleic acid & protein synthesis (DNA
and RNA) by Inhibition of Topoisomerase II. It forms
complexes with DNA by intercalation between base pairs due
to high affinity binding to DNA, It also interferes with DNA
replication and transcription by inhibiting DNA helicase
activity by binding on top of the cell membrane. Hence, it
effects the fluidity of the membrane & cause generation of
free radicals.